Bioassay Technology Laboratory's MICU1 Monoclonal Antibody(Mix) is a Mouse monoclonal antibody. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described